Anaplastic lymphoma of the cervical esophagus presenting as a tracheoesophageal fistula
β Scribed by Anil Joshi; Paul Fields; Ricard Simo
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 302 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1043-3074
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β¦ Synopsis
Abstract
Background
Anaplastic kinaseβ1 positive lymphoma (ALKβ1) is a very rare but distinct pathologic entity. ALKβ1 lymphoma tends to affect the bone marrow, skin, lungs, soft tissue, but very rarely the gastrointestinal tract.
Methods
We report a case of ALKβ1 positive lymphoma presenting as a tracheoesophageal fistula. The clinical presentation, histopathology, and management outcome are all discussed.
Conclusion
ALKβ1 positive lymphoma of the upper aerodigestive involvement is extremely rare. An unusual presentation such as pharyngeal pouch with vocal cord palsy should suggest pathology. Histopathologic analysis can be difficult and immunohistochemical studies will aid are of paramount importance in the diagnosis and help in subsequent management and also act as prognostic indicators. Β© 2008 Wiley Periodicals, Inc. Head Neck, 2008
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