Anaplastic Carcinoma of the Thyroid in a Population Irradiated for Hodgkin Disease, 1910–1960

✍ Scribed by E. Paul Gétaz; Katsutaro Shimaoka

• Publisher: John Wiley and Sons
• Year: 1979
• Tongue: English
• Weight: 567 KB
• Volume: 12
• Category: Article
• ISSN: 0022-4790
• DOI: 10.1002/jso.2930120213

✦ Synopsis

Post-irradiation carcinoma of the thyroid is usually histologically well-differentiated. In general, those subjects who developed carcinoma had been exposed to low-to-moderate doses of irradiation for benign conditions. We reviewed the charts of 520 patients with Hodgkin's disease seen at Roswell Park Memorial Institute, and found 2 cases of anaplastic carcinoma amongst other thyroidal abnormalities. The existing reports of post-irradiation carcinoma are reviewed and suggestions are made for the management of heavily irradiated, potentially cured patients with Hodgkin's disease.