Little is known about the expression of the receptor for complement anaphylatoxin C3a (C3aR) in the central nervous system (CNS). In this study, we provide the first evidence that neurons are the predominant cell type expressing C3aR in the normal CNS. By using in situ hybridization (ISH) and immuno
✦ LIBER ✦
Anaphylatoxin C3a but not C3a(desArg) is a chemotaxin for the mouse macrophage cell line J774
✍ Scribed by Jörg Zwirner; Thomas Werfel; Hans-Christian Wilken; Elgin Theile; Otto Götze
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 135 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0014-2980
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## Abstract Extrahepatic bioartificial liver devices should provide an intact urea cycle to detoxify ammonia. The C3A cell line, a subclone of the hepatoma‐derived HepG2 cell line, is currently used in this context as it produces urea, and this has been assumed to be reflective of ammonia detoxific