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Analyzing drug-resistance in terms of substrate recognition by Hepatitis C Virus NS3 protease

✍ Scribed by Romano, Keith


Book ID
119204880
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
34 KB
Volume
96
Category
Article
ISSN
0006-3495

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Hepatitis C virus (HCV) NS3 protease is responsible for the processing of the viral polyprotein and is considered as a primary target for the development of anti-HCV therapy. We have developed a genetic method in yeast to screen for good substrate sequences of the NS3 protease. A library of fusion p