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Analytical Characteristics of Cleavable Isotope-Coded Affinity Tag-LC-Tandem Mass Spectrometry for Quantitative Proteomic Studies

✍ Scribed by Vaughn, Cecily P.; Crockett, David K.; Lim, Megan S.; Elenitoba-Johnson, Kojo S.J.

Book ID: 121978260
Publisher: American Society for Investigative Pathology
Year: 2006
Tongue: English
Weight: 444 KB
Volume: 8
Category: Article
ISSN: 1525-1578
DOI: 10.2353/jmoldx.2006.060036

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## Abstract The effect of chronic morphine exposure on the synaptic plasma‐membrane subproteome in rats was studied by the isotope‐coded affinity tag (ICAT) method coupled with capillary reversed‐phase liquid chromatography/electrospray ionization mass spectrometry and tandem mass spectrometry. ICA