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Analytical and clinical validity of whole-genome oligonucleotide array comparative genomic hybridization for pediatric patients with mental retardation and developmental delay

✍ Scribed by Bixia Xiang; Ao Li; Dinu Valentin; Norma J. Nowak; Hongyu Zhao; Peining Li


Book ID
102701462
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
561 KB
Volume
146A
Category
Article
ISSN
1552-4825

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## Communicated by Mireille Claustres Genomic imbalance is a major cause of developmental disorders. Microarray-based comparative genomic hybridization (aCGH) has revealed frequent imbalances associated with clinical syndromes, but also a large number of copy number variations (CNVs), which have co