𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Analysis using fluorescence polarization immunoassay for unbound teicoplanin concentration in serum

✍ Scribed by T. Urakami; T. Maiguma; H. Kaji; S. Kondo; D. Teshima


Book ID
108849133
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
181 KB
Volume
33
Category
Article
ISSN
0269-4727

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Impaired protein binding of Chinese medi
✍ Amer Wahed; John Pollard; Alice Wells; Amitava Dasgupta πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 81 KB

## Abstract DanShen is a Chinese medicine that is used to treat cardiovascular disorders. DanShen is moderately to strongly protein bound, mainly to albumin. Because impaired protein binding of albumin‐bound drugs in uremia has been reported, we studied protein binding of DanShen by measuring the d

New Approach for Local Structure Analysi
✍ Suming Chen; Xiaohua Li; Huimin Ma πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 273 KB πŸ‘ 2 views

## Abstract **Designer label**: A newly developed polarity‐sensitive fluorescent probe (DBHA) was combined with a tyrosine‐specific labelling method that uses transition metal catalysis, and was successfully used in local structural analysis of the Tyr108 domain in Cu/Zn superoxide dismutase (SOD;

Saliva and serum samples were collected
Saliva and serum samples were collected from eight healthy volunteers every two hours during a 26-hour period. Melatonin concentrations were measured by radioimmunoassay after chloroform extraction using radioiodinated melatonin as a tracer. Five of the subjects had high serum melatonin levels at night (peak levels higher than 75 pg/ml); in three subjects the highest serum melatonin concentration was 20-40 pg/ml. All subjects had low levels (P <0.001, was obtained for all detectable value pairs (n= 73). The regression and correlation coefficients were almost equal for the peak values of melatonin and during the rising and descending phases of the secretion patterns. However, no significant correlation was found between low daytime salivary and serum concentrations when calculated separately. In the five high-secretors the melatonin levels in saliva reflected reliably the changes in serum, but in the three low-secretors the correlation between salivary and serum melatonin was not significant. The proportion of melatonin found in saliva decreased with increasing serum melatonin levels. Circadian rhythm parameters were estimated by single cosinor analysis. The acrophases did not differ significantly within a subject in the concomitant measurements of serum and salivary melatonin. The measurements of salivary melatonin levels seem valid for studies on melatonin rhythms, but the melatonin concentrations measured in saliva do not always consistently reflect the absolute concentrations in blood.
✍ Maija-Liisa Laakso; Tarja Porkka-Heiskanen; Aino Alila; Dag Stenberg; Gunnar Joh πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 622 KB