Analysis on the association of human BLYS (BAFF, TNFSF13B) polymorphisms with systemic lupus erythematosus and rheumatoid arthritis
β Scribed by Kawasaki, A; Tsuchiya, N; Fukazawa, T; Hashimoto, H; Tokunaga, K
- Book ID
- 110037453
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 133 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1466-4879
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## Abstract ## Objective Genomeβwide association (GWA) studies in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) in Caucasian populations have independently identified risk variants in and near the tumor necrosis factor Ξ± (TNFΞ±)βinduced protein 3 gene (__TNFAIP3__), which is cruc
## Abstract ## Objective. The expression of autoimmunity in mice deficient in programmed death 1 (PDβ1) suggests that PDβ1 is a candidate gene involved in the development of human autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). We therefore tested the