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Analysis of vessel wall morphology, blood flow velocity, and the hemostatic system in a patient with a large intracoronary thrombus

✍ Scribed by Haude, Michael ;Altmann, Christoph ;Eick, Beate ;Liu, Fengqi ;Schwippert, Barbara ;Tschöpe, Diethelm ;Erbel, Raimund

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 271 KB
Volume: 43
Category: Article
ISSN: 0098-6569
DOI: 10.1002/(sici)1097-0304(199803)43:3<298::aid-ccd12>3.0.co;2-i

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✦ Synopsis

A patient with AMI caused by a large thrombus in the proximal LAD was successfully treated with PTCA and an intracoronary lysis combined with the platelet-receptor antagonist c7E3. Analysis of cellular hemostasis after 1 and 6 months revealed a sustained platelet activation despite combined anti-platelet therapy with ASA and ticlopidine. A progredient slow-flow phenomenon appeared during control angiographies, confirmed by intracoronary Doppler examination.