Analysis of urinary oligosaccharides in lysosomal storage disorders by capillary high-performance anion-exchange chromatography–mass spectrometry
✍ Scribed by Bruggink, Cees; Poorthuis, Ben J. H. M.; Deelder, André M.; Wuhrer, Manfred
- Book ID
- 113022034
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 651 KB
- Volume
- 403
- Category
- Article
- ISSN
- 1618-2650
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The on-line coupling of high-performance anion-exchange chromatography (HPAEC) with ion spray mass spectrometry, for the analysis of neutral and acidic oligosaccharides, is described. On-line desalting is performed by a cation-exchange membrane system which replaces sodium for hydronium ions from th
Capillary high performance liquid chromatography (HPLC) was combined with frit fast atom bombardment (FAB) mass spectrometry (MS) and a detailed procedure has been established for on-line analysis of cefaclor in human serum. The capillary column (0.3 mm id.) enabled the introduction of entire efflue