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Analysis of uptake and release of newly synthesized acetylcholine in PC12 cells overexpressing the rat vesicular acetylcholine transporter (VAChT)

โœ Scribed by Ali Roghani; Paul T. Carroll


Book ID
117385856
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
748 KB
Volume
100
Category
Article
ISSN
0169-328X

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Acetylcholine (ACh) is synthesized by choline acetyltransferase (ChAT) in the cytoplasm of cholinergic nerve terminals and transported into synaptic vesicles by vesicular ACh transporter (VAChT). The genes encoding ChAT and VAChT are colocalized within the genome, and their products are known to be