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Analysis of two types of novel alleles in the DXS10011 locus

โœ Scribed by Akiyoshi Tamura; Misa Iwata; Izumi Takase; Tokiko Miyazaki; Kiyoshi Matsui; Hajime Nishio; Koichi Suzuki

Book ID
104039840
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
67 KB
Volume
6
Category
Article
ISSN
1344-6223

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โœฆ Synopsis

A population study of the short tandem repeat locus DXS10011 was carried out in a sample of 104 unrelated Japanese individuals (56 males, 48 females). Thirty-six different alleles were distinguished. The power of discrimination was 0.933 (male) and 0.997 (female). Sequence analysis of alleles was examined for 34 samples. The sequence structures of the alleles were classified into three types: A, B and C. Type A had a regular repeat structure of the repeat region: (GAAA)(n). Types A and B differed in the base sequence of the repeat region. As an A (adenine) insertion in 5' upstream of (GAAA)(n) repeat unit was type C, this type was differentiated from type A.

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