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Analysis of Total Human Immunodeficiency Virus (HIV)-Specific CD4+ and CD8+ T-Cell Responses: Relationship to Viral Load in Untreated HIV Infection

✍ Scribed by Betts, M. R.; Ambrozak, D. R.; Douek, D. C.; Bonhoeffer, S.; Brenchley, J. M.; Casazza, J. P.; Koup, R. A.; Picker, L. J.


Book ID
126503421
Publisher
American Society for Microbiology
Year
2001
Tongue
English
Weight
756 KB
Volume
75
Category
Article
ISSN
0022-538X

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## Abstract Recent studies indicate that a defective proliferative response of HIV‐specific CD8+ T cells is associated with the lack of virologic control in chronic HIV infection in humans. The possible mechanisms that might be responsible for the reduced proliferative potential of HIV‐specific CD8