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Analysis of three genetic polymorphisms as risk factors for thrombosis

✍ Scribed by P. Giordano; B. Coppola; A. Iolascon; M. Micelli; P. Trerotoli; D. De Lucia


Book ID
106194940
Publisher
Springer
Year
1999
Tongue
English
Weight
196 KB
Volume
29
Category
Article
ISSN
0940-5437

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✍ Ou, C Y; Stevenson, R E; Brown, V K; Schwartz, C E; Allen, W P; Khoury, M J; Roz πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 19 KB πŸ‘ 2 views

Persons with a thermolabile form of the enzyme 5,lO methylenetetrahydrofolate reductase (MTHFR) have reduced enzyme activity and increased plasma homocysteine which can be lowered by supplemental folic acid. Thermolability of the enzyme has recently been shown to be caused by a common mutation (677C