Analysis of the α-synuclein G209A mutation in familial Parkinson's disease
✍ Scribed by Sepideh Zareparsi; Jeffrey Kay; Richard Camicioli; Patricia Kramer; John Nutt; Thomas Bird; Michael Litt; Haydeh Payami
- Book ID
- 117296808
- Publisher
- The Lancet
- Year
- 1998
- Tongue
- English
- Weight
- 59 KB
- Volume
- 351
- Category
- Article
- ISSN
- 0140-6736
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Recent interest has focused on the largest pedigree reported to date with histologically proven Lewy body parkinsonism with an autosomal-dominant mode of transmission.' It consisted of descendants of several immigrants to the United States linked to collateral Italian descendants by a common ancesto
## Abstract The motor and neuropsychological abnormalities in eight Greek patients with Parkinson's disease (PD) carrying the α‐synuclein gene mutation (G209A) were studied. These patients (five men, three women) belonged to six different families. Their symptoms started between 32–50 years of age