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Analysis of the serotonin transporter polymorphism (5-HTTLPR) in Brazilian patients affected by dysthymia, major depression and bipolar disorder

✍ Scribed by Oliveira, J R M; Carvalho, D R; Pontual, D; Gallindo, R M; Sougey, E B; Gentil, V; Lafer, B; Maia, L G S; Morais, M A; Matioli, S


Book ID
110059190
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
118 KB
Volume
5
Category
Article
ISSN
1359-4184

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Analysis of a novel functional polymorph
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It has been suggested that the serotonin transporter (5-hydroxytryptamine-transporter or 5-HTT) may be involved in the pathogenesis of affective disorders. Recently, Collier et al. (1996) found that the frequency of the low-activity short variant (s) of the 5-HTT-linked polymorphic region (5-HTTLPR)