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ANALYSIS OF THE ROLE OF MTHFR C677T AND TGF-BETA C-509T POLYMORPHISMS IN TYPE 1 DIABETIC PATIENTS WITH CHRONIC RENAL FAILURE

✍ Scribed by Tecuceanu, C.I.; Cimponeriu, D.; Apostol, P.; Stavarachi, M.; Toma, M.; Usurelu, D.; Craciun, A.M.; Letitia, D.; Gavrila, L.; Cheta, D.

Book ID
118636281
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
71 KB
Volume
9
Category
Article
ISSN
1567-5688

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## Abstract ## Background Poor glycaemic control, hypertension and duration of diabetes are risk factors for the development of diabetic nephropathy, but there may be genetic factors. Recently, a common C to T mutation at nucleotide position 677 of the MTHFR gene (MTHFR677C > T) has been reported