A gas chromatography/mass spectrometry (GC/MS) method is described which uses negative ion chemical ionization (NCI) and tandem mass spectrometry (MS/MS) for the determination of eight anabolic steroids in human urine. Eight anabolic steroids were derivatized by heptafluorobutyric anhydride (HFBA),
Analysis of the pentafluorobenzoyl derivative of phenylethylamine utilizing negative ion chemical ionization and gas chromatography/mass spectrometry
β Scribed by Peter Gashkoff; Reuben Matalon; Vincent Papa; Dana Sebasta
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 212 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1076-5174
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Gas chromatography-negative chemical ionization mass spectrometry (GC-NCIMS) has been applied to the analysis of 0-and S-glucuronides. The glucuronides were derivatized with pentafluorobenzyl (PFB) bromide and Tri-Sil, and analyzed by GC-NCIMS. All glucuronides gave a large [M-PFBI-ion indicative of