Analysis of the P300/CBP-Associated Factor (PCAF) Gene in Astrocytic Tumors
โ Scribed by Hiroyuki Nishimori; Ryo Nishikawa; Takamitsu Fujimaki; Tadayoshi Nakagomi; Masao Matsutani; H.-J. Su Huang; Webster K. Cavenee
- Book ID
- 110235043
- Publisher
- Springer US
- Year
- 2000
- Tongue
- English
- Weight
- 39 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0167-594X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Histone N-acetyltransferases (HATs) are a group of enzymes which acetylate specific lysine residues in the N-terminal tails of nucleosomal histones to promote transcriptional activation. Recent structural and enzymatic work on the GCN5/PCAF HAT family has elucidated the structure of their catalytic
Mutation of the p53 gene is found in about one third of astrocytic brain tumors, and expansion of tumor cell clones containing mutant p53 has been implicated in astrocytic tumor progression. However, admixture of normal cells in astrocytic tumor specimens limits the power of traditional studies of t
The inhibitors of DNA binding (Id) gene family is highly expressed during embryogenesis and throughout adulthood in the rat central nervous system (CNS). In vitro studies suggest that the Id gene family is involved in the regulation of cell proliferation and differentiation. Recently, Id gene expres