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Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

โœ Scribed by Kamb, A.; Shattuck-Eidens, D.; Eeles, R.; Liu, Q.; Gruis, N. A.; Ding, W.; Hussey, C.; Tran, T.; Miki, Y.; Weaver-Feldhaus, J.


Book ID
109917893
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
586 KB
Volume
8
Category
Article
ISSN
1061-4036

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Deletion mapping of chromosome region 9p
โœ Masataka Ohta; David Berd; Masayoshi Shimizu; Hirokazu Nagai; Maria-Grazia Cotti ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 750 KB

The cyclin-dependent kinase-4 inhibitor gene CDKN2, localized at chromosome region 9 ~2 1 , has been shown to be a familial melanoma gene, though we found that mutations of it are rare in uncultured sporadic melanomas. To determine whether the region of allelic loss at 9p2 I frequently observed in s