𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Analysis of the NF1 gene by temperature gradient gel electrophoresis reveals a high incidence of mutations in exon 4b

✍ Scribed by Mohammed R. Toliat; Fikret Erdogan; Andreas Gewies; Raimund Fahsold; Annegret Buske; Sigrid Tinschert; Peter Nürnberg


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
116 KB
Volume
21
Category
Article
ISSN
0173-0835

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


A novel mutation L1425p in the GAP-regio
✍ Hartmut Peters; D. Hess; R. Fahsold; M. Schülke 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 43 KB

Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with an incidence of between 1: 3000 and 1: 4000. Common clinical signs include more than six café-au-lait spots, multiple cutaneous neurofibromas and iris Lisch nodules. Rarer are skeletal anomalies, learning disabilities and an incre

Complete scanning of the CDK4 gene by de
✍ Per Guldberg; Alexei F. Kirkin; Kirsten Grønbæk; Per thor Straten; Vibeke Ahrenk 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 60 KB 👁 1 views

The cyclin-dependent kinase 4 (CDK4) is a key component in regulation of the mammalian cell cycle. The recent discovery of a common missense mutation (Arg24Cys) in both sporadic and familial forms of malignant melanoma strongly supports the candidacy of CDK4 as a proto-oncogene. To study further the