Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with an incidence of between 1: 3000 and 1: 4000. Common clinical signs include more than six café-au-lait spots, multiple cutaneous neurofibromas and iris Lisch nodules. Rarer are skeletal anomalies, learning disabilities and an incre
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Analysis of the NF1 gene by temperature gradient gel electrophoresis reveals a high incidence of mutations in exon 4b
✍ Scribed by Mohammed R. Toliat; Fikret Erdogan; Andreas Gewies; Raimund Fahsold; Annegret Buske; Sigrid Tinschert; Peter Nürnberg
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 116 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0173-0835
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