Analysis of the interplay among charge, hydration and shape of proteins through the modeling of their CZE mobility data
β Scribed by Maria V. Piaggio; Marta B. Peirotti; Julio A. Deiber
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 174 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0173-0835
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## Abstract Peptide electrophoretic mobility data are interpreted through a physicochemical CZE model, providing estimates of the equivalent hydrodynamic radius, hydration, effective and total charge numbers, actual ionizing p__K__, pHβnear molecule and electrical permittivity of peptide domain, am
## Abstract This work explores the validity of simple CZE models to analyze the electrophoretic mobilities of 102β peptides reported in literature. These models are based mainly on fundamental physicochemical theories providing analytical expressions amenable to relatively simple numerical analysis.