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Analysis of the genes coding for the BRCA1-interacting proteins, RAP80 and Abraxas (CCDC98), in high-risk, non-BRCA1/2, multiethnic breast cancer cases

✍ Scribed by David J. Novak; Nelly Sabbaghian; Philippe Maillet; Pierre O. Chappuis; William D. Foulkes; Marc Tischkowitz


Book ID
106377904
Publisher
Springer US
Year
2008
Tongue
English
Weight
184 KB
Volume
117
Category
Article
ISSN
0167-6806

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## Abstract Our current understanding of breast cancer susceptibility involves mutations in the 2 major genes __BRCA1__ and __BRCA2__, found in about 25% of high‐risk families, as well as few other low penetrance genes such as __ATM__ and __CHEK2__. Approximately two‐thirds of the multiple cases fa