Genetic variants and haplotype analyses
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Sylvie Desjardins; Pascal Belleau; Yvan Labrie; Geneviève Ouellette; Paul Besset
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Article
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2008
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John Wiley and Sons
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French
⚖ 214 KB
👁 1 views
## Abstract Our current understanding of breast cancer susceptibility involves mutations in the 2 major genes __BRCA1__ and __BRCA2__, found in about 25% of high‐risk families, as well as few other low penetrance genes such as __ATM__ and __CHEK2__. Approximately two‐thirds of the multiple cases fa