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Analysis of the fibrillin-1 gene (FBN1) in patients with Marfan syndrome

✍ Scribed by R. R. Valiev; R. I. Khusainova; I. A. Kutuev; E. K. Khusnutdinova


Book ID
110174401
Publisher
SP MAIK Nauka/Interperiodica
Year
2006
Tongue
English
Weight
223 KB
Volume
40
Category
Article
ISSN
0026-8933

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## Communicated by Jurgen Horst Marfan syndrome (MFS) is an autosomal-dominant disorder of the fibrous connective tissue that is typically caused by mutations in the gene coding for fibrillin-1 (FBN1), a major component of extracellular microfibrils. The clinical spectrum of MFS is highly variable