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Analysis of the effect of local interactions on protein stability

✍ Scribed by Victor Muñoz; Philippe Cronet; Eva López-Hernéndez; Luis Serrano


Book ID
114382570
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
701 KB
Volume
1
Category
Article
ISSN
1359-0278

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## Abstract Thermal stability shift analysis is a powerful method for examining binding interactions in proteins. We demonstrate that under certain circumstances, protein–protein interactions can be quantitated by monitoring shifts in thermal stability using thermodynamic models and data analysis m