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Analysis of the Cellular Requirements for the Binding of Exogenous Peptides to MHC Class II Molecules

✍ Scribed by G. Poirier; B. Chain


Book ID
112238826
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
413 KB
Volume
152
Category
Article
ISSN
0008-8749

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The peptide-binding strategy of the MHC
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he allele-specific peptidebinding motifs of major histocompatibility complex (MHC) proteins, originally discovered by pool sequencing of MHC class I-bound peptides 1 , provide a biochemical basis for the phenomenon of MHC restriction of T-cell responses. However, the analysis of class II peptide mot