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Analysis of the candidate 8p21 tumour suppressor, BNIP3L, in breast and ovarian cancer

✍ Scribed by Lai, J; Flanagan, J; Phillips, W A; Chenevix-Trench, G; Arnold, J

Book ID: 109997438
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 164 KB
Volume: 88
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6600674

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## Abstract Extensive hypermethylation and consecutive transcriptional silencing of tumorsuppressor genes have been documented in multiple tumor entities including breast cancer. In a microarray based genome‐wide methylation analysis of five sporadic breast carcinomas we identified a hypermethylate