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Analysis of the bHLH Transcription Factors Olig1 and Olig2 in Brain Tumors

✍ Scribed by Lucinda Aguirre-Cruz; Karima Mokhtari; Khê Hoang-Xuan; Yannick Marie; Emmanuelle Criniere; Sophie Taillibert; Manuel Lopes; Jean-Yves Delattre; Marc Sanson


Book ID
111601870
Publisher
Springer US
Year
2004
Tongue
English
Weight
214 KB
Volume
67
Category
Article
ISSN
0167-594X

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## Abstract The capacity of adult human glial progenitor cells (AGPs), to proliferate and undergo multipotent differentiation, positions them as ideal candidate cells of origin for human gliomas. To investigate this potential role we identified AGPs as mitotically active Olig2 cells in nonneoplasti