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Analysis of the base excision repair genes MTH1, OGG1 and MUTYH in patients with squamous oral carcinomas

✍ Scribed by Heike Görgens; Annegret Müller; Stefan Krüger; Eberhard Kuhlisch; Inke R. König; Andreas Ziegler; Hans K. Schackert; Uwe Eckelt


Book ID
113832819
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
119 KB
Volume
43
Category
Article
ISSN
1368-8375

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Genetic polymorphisms in DNA base-excisi
✍ Chunying Li; Zhibin Hu; Jiachun Lu; Zhensheng Liu; Li-E Wang; Adel K. El-Naggar; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 242 KB 👁 2 views

## Abstract ## BACKGROUND. Tobacco smoke contains numerous carcinogens that cause DNA damage, including oxidative lesions that are removed effectively by the base‐excision repair (BER) pathway, in which adenosine diphosphate ribosyl transferase (ADPRT), x‐ray repair cross‐complementing 1 (XRCC1),