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Analysis of the apo E/apo C-I, angiotensin converting enzyme and methylenetetrahydrofolate reductase genes as candidates affecting human longevity

โœ Scribed by Daliah Galinsky; Carolyn Tysoe; Carol E. Brayne; Douglas F. Easton; Felicia A. Huppert; Thomas R. Dening; Eugene S. Paykel; David C. Rubinsztein

Book ID
119436278
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
250 KB
Volume
129
Category
Article
ISSN
0021-9150

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The genetic factors which predispose individuals to dementia in old age have not been fully defined. Although the apolipoprotein E4 allele accounts for a proportion of the genetic risk for late-onset Alzheimer disease (AD), it is neither necessary nor sufficient to cause this disease. Recent suggest