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Analysis of the 5′-flanking promoter region of the 5-HT2A receptor gene in schizophrenia

✍ Scribed by Koichi Ohara; Atsushi Ino; Tatsuya Ishigaki; Kunihiko Tani; Toshio Tsukamoto; Yuhei Nakamura; Kenshiro Ohara

Book ID: 114282167
Publisher: Nature Publishing Group
Year: 1997
Tongue: English
Weight: 630 KB
Volume: 17
Category: Article
ISSN: 1470-634X
DOI: 10.1016/s0893-133x(97)00052-3

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Dysfunction of serotonin systems has been implicated in schizophrenia. In the present study, the human 5-HT 1A receptor gene containing the 5 untranslated region was screened in order to detect genetic variations, through which alteration of protein function or level of expression might contribute t