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Analysis of Rex1 (zfp42) function in embryonic stem cell differentiation

โœ Scribed by Kymora B. Scotland; Siming Chen; Renia Sylvester; Lorraine J. Gudas

Book ID
102818103
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
1014 KB
Volume
238
Category
Article
ISSN
1058-8388

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## Abstract Rex1 (zfp42) was identified by our laboratory because of its reduced expression in F9 teratocarcinoma stem cells after retinoic acid (RA) treatment. The Rex1 (Zfp42) gene is currently widely used as a marker of embryonic stem cells. We compared the transcriptional regulation of the huma

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Human Rex-1 (hRex-1) (also referred to as zinc-finger protein-42, Zfp42) encodes a zinc finger protein expression of which is believed to be characteristic of pluripotent stem cells. We have applied bioinformatics to classify the relationship of human, rat, and mouse REX1 proteins in the C2H2 family