Autonomous parvovirus vectors: preventin
Autonomous parvovirus vectors: preventing the generation of wild-type or replication-competent virus
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Annick Brandenburger; Thierry Velu
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Article
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2004
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John Wiley and Sons
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English
โ 186 KB
The preferential expression of autonomous parvoviruses in tumour cells and their oncolytic activity has attracted attention to the potential use of these viruses as vectors for cancer gene therapy. Moreover, they are non-pathogenic in adult animals and they seem to be associated with low or no immun