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Analysis of polymerase chain reaction product by capillary electrophoresis and its application to the detection of single base substitution in genes

✍ Scribed by Hidetoshi Arakawa; Kunio Uetanaka; Masako Maeda; Akio Tsuji


Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
731 KB
Volume
664
Category
Article
ISSN
1873-3778

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A clonal-specific polymerase chain reaction technique to detect T-cell receptor delta gene rearrangement in acute lymphoblastic leukaemia (ALL) and non-Hodgkin's lymphoma (NHL) was evaluated. It was applied to detect minimal residual disease. A sensitive and specific technique to detect minimal resi