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Analysis of plasmin binding and urokinase activation of plasminogen bound to the heymann nephritis autoantigen, gp330

✍ Scribed by John J. Kanalas


Book ID
115709148
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
676 KB
Volume
299
Category
Article
ISSN
0003-9861

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Molecular assembly of plasminogen and tissue-type plasminogen actwator (t-PA) at the surface of fibrin results in the generation of fibrin-bound plasmin and thereby in the dissolution of a clot. This mechanism is triggered by specific interactions of intra-chain surface lysine residues in fibrin wit