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Analysis of organophosphorus compound adducts of serine proteases by liquid chromatography–tandem mass spectrometry

✍ Scribed by Kouichiro Tsuge; Yasuo Seto

Book ID
108497288
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
755 KB
Volume
776
Category
Article
ISSN
1873-376X

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## Abstract Endogenous carcinogens arising from normal metabolism are known to cause modifications to DNA by reacting with bases to form adducts. Malondialdehyde is a well characterized endogenous carcinogen that forms an adduct with 2′‐deoxyguanosine. This adduct has been detected in rat and human