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Analysis of nucleosides, nucleotides and oligonucleotides using fast atom bombardment mass spectrometry

โœ Scribed by Karl H. Schram

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
631 KB
Volume
7
Category
Article
ISSN
0165-9936

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The effect of trimethylsilyl (TMS) derivatization on detection limits of mononucleotides in fast atom bombardment-mass spectrometry (FAB-MS) was examined. FAB-MS methods were developed to optimize sensitivity using adenosine 6'-monophosphate as a model compound and then applied to reference standard