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Analysis of neurochemical mechanisms of the psychotropic action of tuftsin and its analogs

โœ Scribed by A. V. Val'dman; N. A. Bondarenko; V. A. Kamysheva; M. M. Kozlovskaya; V. N. Kalikhevich; Z. A. Ardemasova


Publisher
Springer US
Year
1982
Tongue
English
Weight
390 KB
Volume
93
Category
Article
ISSN
0007-4888

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Incubation of human polymorphonuclear leukocytes (PMNL) or thioglycollate-stimulated mouse peritoneal macrophages with the phagocytosis-stimulating peptide, tuftsin (2.5 X 10(-7) M, at 37 degrees C), caused an increase of 80-90% in intracellular cGMP levels, accompanied by a decrease of 20-25% in in