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Analysis of neural tube defects in a mouse mutant using whole embryo culture

โœ Scribed by Copp, A.J.; Shum, A.S.W.; Brook, F.A.

Book ID
122815631
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
467 KB
Volume
7
Category
Article
ISSN
0887-2333

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## Abstract Early somite mouse embryos were exposed in vitro to xylocaine (Lignocaine hydrochloride) to examine its effect on neural tube closure. When embryos were exposed to 2.4 ร— 10^โˆ’4^ mg/ml xylocaine for the entire 36โ€hour culture period, cephalic neural tube closure did not take place. When e