Ranitidine hydrochloride (RAN-HCl), a known anti-ulcer drug, is the product of reaction between HCl and ranitidine base (RAN-B). RAN-HCl has been extensively studied; however this is not the case of the RAN-B. The solid state characterization of RAN-B polymorphs has been carried out using different
Analysis of N-(4-hydroxyphenyl)retinamide polymorphic forms by X-ray powder diffraction
β Scribed by F. A. Chrzanowski; B. J. Fegely; W. R. Sisco; M. P. Newton
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 317 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0022-3549
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β¦ Synopsis
A quantitative X-ray diffraction method, with zinc oxide used as the internal standard, was developed for the analysis of polymorphic forms I and II of N-(4-hydroxyphenyl)retinamide. The standard curve relating peak height ratio to the percentage of form I was linear. The method was precise and accurate to within +/- 6%.
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A detection limit of 0.05% quartz in calcitic and dolomitic carbonate and talc matrices is dependent upon significant counting time for optimal signal to noise ratio, utilization of peak area counts, absence of significant interfering phase(s), a known blank ( < 0.05%) for each matrix, statistically