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Analysis of mutational status, SNP rs16754, and expression levels of Wilms tumor 1 (WT1) gene in acute promyelocytic leukemia

✍ Scribed by Girish Chander Gaur, Safaa M. Ramadan, Laura Cicconi…

Book ID: 120775637
Publisher: Springer
Year: 2012
Tongue: English
Weight: 152 KB
Volume: 91
Category: Article
ISSN: 0939-5555
DOI: 10.1007/s00277-012-1546-7

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## Abstract The Wilms' tumor 1 gene, __WT1__, encodes a zinc‐finger protein that is implicated in the development of Wilms' tumor. Mutant or aberrantly expressed WT1 isoforms have also been described in desmoplastic small round cell tumor, acute leukemias, mesothelioma, breast tumors and melanoma.