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Analysis of Molecular Recognition Features (MoRFs)

โœ Scribed by Amrita Mohan; Christopher J. Oldfield; Predrag Radivojac; Vladimir Vacic; Marc S. Cortese; A. Keith Dunker; Vladimir N. Uversky

Book ID
116663230
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
754 KB
Volume
362
Category
Article
ISSN
0022-2836

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The phenomenon of molecular recognition depends strongly on surface complementarity between associating molecular units, analogous to the assembly of a threedimensional jigsaw puzzle. The driving force for association is solvent entropy, which increases when protrusions of the irregular surface of o