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Analysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma

✍ Scribed by Georges Maire; Jeff W. Martin; Maisa Yoshimoto; Susan Chilton-MacNeill; Maria Zielenska; Jeremy A. Squire


Book ID
116332569
Publisher
Elsevier
Year
2011
Tongue
English
Weight
382 KB
Volume
204
Category
Article
ISSN
2210-7762

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## Abstract It is thought that altered microRNA (miRNA) expression due to various mechanisms plays a critical role in the pathogenesis of most human cancers. Notably, about half of the known miRNAs are intragenic and frequently coexpressed with their host genes. To date there is little evidence con