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Analysis of micronuclei induced by 1,3-butadiene and its metabolites using fluorescence in situ hybridization

✍ Scribed by Y. Xiao; J.M. de Stoppelaar; B. Hoebee; G. Schriever-Schwemmer; I.-D. Adler; A.D. Tates


Book ID
113194938
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
816 KB
Volume
354
Category
Article
ISSN
0027-5107

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Germ cell mutagenicity of three metaboli
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Three metabolites of the industrial chemical 1,3-butadiene (BD), namely butadiene monoepoxide (BMO, 3,4-epoxy-1-butene), diepoxide (DEB, 1,2;3,4-diepoxybutane), and diolepoxide (DE, 3,4- epoxybutane-1,2-diol) were studied for germ cell mutagenicity using the rat spermatid micronucleus (MN) test. All