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Analysis of membrane bilayer asymmetry using parinaric acid fluorescent probes

โœ Scribed by Larry A. Sklar; Edward A. Dratz


Book ID
115910753
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
286 KB
Volume
118
Category
Article
ISSN
0014-5793

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cis-Parinaric acid (PnA), cis-trans-trans-cis-9, 11, 13, 15-octadecatetraenoic acid, is fluorescent (epsilon = 74,000 at 324 nm) when partitioned into a lipid environment and the fluorescence is destroyed upon reaction with free radicals. It has been used to monitor semiquantitatively free-radical-i