Analysis of meiotic segregation in a man heterozygous for a 13;15 Robertsonian translocation and a review of the literature
β Scribed by Franck Pellestor
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 759 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0340-6717
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The frequencies of aneuploid and diploid sperm were determined in a 47,XYY male using multi-color fluorescence in situ hybridization (FISH) analysis, and compared with those from 10 control donors. A total of 30,078 sperm from the patient was scored, 15,044 by two-color FISH for chromosomes 13 and 2
The Leuven cytogenetic centre experience on pericentric inversion in man is discussed with exclusion of the pericentric inversions of the heterochromatic blocks of chromosomes 1 and 9. In a total of 51,500 patients, referred for constitutional chromosome analysis during the period 1970-1985, pericen