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Analysis of low-abundance proteins using the proteomic reactor with pH fractionation

✍ Scribed by Hu Zhou; Weimin Hou; Jean-Philippe Lambert; Ruijun Tian; Daniel Figeys

Book ID
116903907
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
951 KB
Volume
80
Category
Article
ISSN
0039-9140

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## Abstract Plasma is an important biological material for biomarker discovery. However, the wide dynamic range in protein concentration remains a major challenge. In this paper, we introduce the development of a proteomic platform for analysis of plasma samples. The method utilizes a double fracti