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Analysis of longitudinal data from twins

✍ Scribed by R.M. Huggins; N.H. Hoang; D.Z. Loesch

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
140 KB
Volume
19
Category
Article
ISSN
0741-0395

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✦ Synopsis

Longitudinal data from twin pairs may be used to determine how the genetic effects influencing a quantitative trait change with age. Here a model for mixed longitudinal data of Huggins and Loesch [1998] on unrelated individuals is extended to twin studies. The model is fitted using robust statistical methods and a bootstrap procedure is proposed to estimate the percentiles. The method is applied to longitudinal twin data on body mass index in male and female twin pairs aged 5-18 years.

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