The effect of antagonists on the conform
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Jianyun Lu; Marcia I. Dawson; Qiong Ying Hu; Zebin Xia; Jesse D. Dambacher; Mao
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Article
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2009
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John Wiley and Sons
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English
⚖ 571 KB
## Abstract The effect of retinoid X receptor (RXR) antagonists on the conformational exchange of the RXR ligand‐binding domain (LBD) remains poorly characterized. To address this question, we used nuclear magnetic resonance spectroscopy to compare the chemical shift perturbations induced by RXR an