## Abstract The high surface area monolith with reactive hydroxyl group on its surface enables it to function as a miniature solid‐phase extraction (SPE) cartridge in size of 1 cm in diameter and 0.5 cm in length. The prepared silica monolith was characterized by Brunauer–Emmett–Teller method, scan
Analysis of ketamine and norketamine in hair samples using molecularly imprinted solid-phase extraction (MISPE) and liquid chromatography–tandem mass spectrometry (LC-MS/MS)
✍ Scribed by Norlida Harun; Robert A. Anderson; Peter A. G. Cormack
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 262 KB
- Volume
- 396
- Category
- Article
- ISSN
- 1618-2650
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Three online solid phase extraction‐liquid chromatography‐tandem mass spectrometry (SPE‐LC‐MS/MS) method examples are presented where two different types of chromatographic columns or solvent systems were coupled to meet specific analytical objectives: (i) SPE of target analytes by rest
Presence of matrix ions could negatively affect the sensitivity and selectivity of liquid chromatography-tandem mass spectrometer (LC-MS/MS). In this study, the efficiency of a miniaturized silica monolithic cartridge in reducing matrix ions was demonstrated in the simultaneous extraction of morphin